Program letne konference CIPKEBIP 2011 »Biosintezni in metabolni inženiring pri razvoju zdravil in procesov v industriji«

15. september, 2011
Institut Jožef Stefan, Jamova cesta 39, Ljubljana, Velika predavalnica
09:00 – 09:30	registracija
Predsedujoča: Enej Kuščer, Hrvoje Petković
Otvoritev konference
09:30 – 10:00	pozdravni nagovor
	Dušan Turk, strokovni direktor CIPKeBiP Jadran Lenarčič, direktor IJS Urban Krajcar, Ministrstvo za visoko šolstvo, znanost in tehnologijo
10:00 – 10:45	uvodno predavanje: Oxytetracycline - from discovery to genome sequence	Iain S. Hunter
10:45 – 11:00	odmor za kavo
11:00-13:40	Sekcija 1 »Biosintetski inženiring in razvoj zdravil«
11:00-11.30	Macrolides - more than antibiotics	Vesna Eraković Haber
11:30-12:00	Towards novel modular polyketide synthases- lessons learnt from evolution	John Cullum
12:00-12:10	odmor za kavo
12:10-12:40	Biosynthetic Engineering Approaches to Natural Product Lead Optimization	Steve Kendrew
12:40-13:10	Genomic data analysis - "What would Google do?"	Daslav Hranueli
13:10-13:40	Exploring modularity - Cooperating fungal iterative polyketide synthases for resorcylic acid lactone production	Istvan Molnar
13:40 – 14:40	kosilo
14:40-15:10	Sekcija 2 »Predstavitev centrov odličnosti CO ENFIST in CO BIK«
14:40-14:55	Predstavitev dosežkov CO ENFIST	Matjaž Polak
14:55-15:10	Predstavitev dosežkov CO BIK	Rebeka Koncilja
15:10-18:20	Sekcija 3 »Biologija aktinomicetes in razvoj industrijskih procesov«
15:10-15:40	Manipulation of streptomycete mycelial architecture	Paul Herron
15:40-16:10	Improved erythromycin A production and purity by modulation of the overexpression of tailoring genes eryK and eryG in Saccharopolyspora erythraea and their fermentation optimization	Ju Chu
16:10-16:20	odmor za kavo
16:20-16:50	New insights into substrate supply and regulation of FK506 Biosynthesis and their implications for Bioprocess development and drug discovery	Gregor Kosec
16:50-17:20	Improvement of Oxytetracycline Production by Using Different Genetic Engineering Strategies	Meijin Guo
17:20-17:50	Streptomycetes are a source of hydrolytic enzymes with potential in lipid biotransformation	Dušica Vujaklija
Zaključek prvega dne konference: Enej Kuščer, Hrvoje Petković
16. september, 2011
Institut Jožef Stefan, Jamova cesta 39, Ljubljana, Velika predavalnica
09:00 – 09:30	registracija
Predsedujoči: Dušan Turk
9:30-14:35	Predstavitve raziskovalnega dela v okviru CIPKEBIP v letu 2011
09:30 – 10:15	DS 1: Mehanizmi in poti pri imunskem odzivu
	Overview	Maja Rupnik
		Tatjana Lejko
10:15 – 11:00	DS 2: Znotraj in zunaj celična komunikacija
10:15 – 10:24	Development of novel bioactive compounds by biosynthetic and chemobiosynthetic approaches	Enej Kuščer
10:24 – 10:33	Role of cathepsins in cancerogenesis	Marko Fonović
10:33 – 10:42	Super-resolution Microscopy and Cell Physiology	Marko Kreft
10:42 – 10:51	Organelle mediated signaling in endocrine tissue models	Marjan Slak Rupnik
10:51 – 11:00	Secreted Phospholipases A2 and Breast Cancer	Jože Pungerčar
11:00 – 11.15	odmor za kavo
11:15 – 12:35	DS 3: Prilagoditveni mehanizmi ekstremofilov na okolje
	Overview	Nina Gunde Cimerman
		Nataša Poklar Ulrih
	DS 4: Proteinska banka: proizvodnja in shranjevanje proteinov in proteinskih kompleksov
	Protein Data Bank: Overview	Dušan Turk
12:35 – 13:20	kosilo
13:20 – 14:20	5 minutne predstavitve raziskovalnega dela v letu 2011
	Vpliv sevov bakterije Clostridium difficile s hemolitično aktivnostjo na aktinski citoskelet	Mateja Zemljič (DS1)
	How does a sales oriented company start its R&D activities?	Mateja Štempelj (DS2)
	Lipid signaling molecules attenuate vesicle mobility in cultured rat astrocytes	Saša Trkov (DS2)
	Calcium Dynamics of Langerhans´ Islets in Pancreas Tissue Slices	Andraž Stožer (DS2)
	Chemistry in alternative reaction media: Effect of physico-chemical parameters and interactions on reactivity and selectivity (presentation of previous research work)	Ajda Podgoršek (DS2)
	The mechanism of HAL2 salt tolerance in fungi living in extreme saline environment	Metka Lenassi (DS3)
	Identifying genes for the improvement of plant stress tolerance	Cene Gostinčar (DS3)
	Technologies and methodologies behind the DS4 – Protein production and structure determination pipeline	Marko Mihelič (DS4)
	Automatic protein function prediction	Bernard Ženko (DS4)
	Ectopic expression of group X secreted phospholipase A2 induces proliferation of highly invasive and tumorigenic breast cancer cells	Toni Petan (DS2)
	Proteomics of Vipera a. ammodytes and Conus consors venoms	Adrijana Leonardi (DS2)
	Structural biology of Clostridium difficile virulence factors	Aleksandra Usenik (DS1)
14:20 – 14:35	odmor za kavo
14:35 -18:00	Predstavitve proizvajalcev opreme in njihovih slovenskih zastopnikov
14.35 - 14:50	Bia d.o.o.	Petra Draškovič, Malan Štrbec
14:50 - 15:05	LKB Vertriebs GmbH	Richard Feike
15:05 - 15:20	Mikro+Polo d.o.o.	Tomaž Hočevar
15:20 - 15:35	Mettler Toledo d.o.o.	Keith Racman
Zaključek drugega dne konference: Dušan Turk